Medical Cannabis

Opioid & Cannabinoid Pharmacokinetic Interactions of Cannabis Drug

If patients have cancer and feel chronic pain, cancer can become seriously problematic and painful. Some Opioid’s are effective analgesics but can cause nausea and other negative side effects. Dr. Donald Abrams has proven that Cannabis treats the chronic pain of cancer patients, with limited side effects. Researcher’s view: Dr. Donald Abrams conducted this study to show the interaction of opioid and Cannabinoid in a cancer patient. Donald Abrams is the chief of Hematology/Oncology Division at the General Hospital of San Francisco. Dr. Donald Abrams discusses the interaction of opioid and Cannabinoid in this quote from his book: “The anti-nociceptive effects of morphine are predominantly mediated by mu receptors but may be enhanced by delta-9-THC activation of kappa and delta opioid receptors (Manzanares et al., 1999). It has been further postulated that the cannabinoid: opioid interaction may occur at the level of their signal trans-duction mechanisms (Pugh, Smith, Dombrowski, & …

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