Opioid & Cannabinoid Pharmacokinetic Interactions of Cannabis Drug

icon  16 Feb, 2015  /  icon  14

If patients have cancer and feel chronic pain, cancer can become seriously problematic and painful. Some Opioid’s are effective analgesics but can cause nausea and other negative side effects. Dr. Donald Abrams has proven that Cannabis treats the chronic pain of cancer patients, with limited side effects.

Researcher’s view:

Dr. Donald Abrams conducted this study to show the interaction of opioid and Cannabinoid in a cancer patient. Donald Abrams is the chief of Hematology/Oncology Division at the General Hospital of San Francisco. Dr. Donald Abrams discusses the interaction of opioid and Cannabinoid in this quote from his book:

“The anti-nociceptive effects of morphine are predominantly mediated by mu receptors but may be enhanced by delta-9-THC activation of kappa and delta opioid receptors (Manzanares et al., 1999). It has been further postulated that the cannabinoid: opioid interaction may occur at the level of their signal trans-duction mechanisms (Pugh, Smith, Dombrowski, & Welch, 1996; Welch & Stevens, 1992). Receptors for both classes of drugs are coupled to similar intra-cellular signaling mechanisms that lead to a decrease in cAMP production by way of G, protein activation (Pugh, Welch, & Bass, 1994; Welch & Eads, 1999; Welch, Thomas, & Patrick, 1995). ‘’

Donald Abrams conducted a pharmacokinetic interaction to identify the effect of medical cannabis on disposition kinetic of opioid analgesics. There are no adverse effects of combining opioids and cannabinoids which was observed over much research and patient evaluation.

Purpose of the study

 The study was put forth to assess the positive effects of smoking marijuana for cancer patients. Cannabis drug effects the patient’s absorption, metabolism, distribution and excretion of largely used opioid analgesics.

Medical cannabis is generally in taken by smoking, for medical use. Marijuana contains Cannabinoid and THC (tetrahydrocannabinol). FDA approved medical cannabis for the treatment weight loss, cancer and chronic pain. People generally buy Medical marijuana in California from Cannabis Dispensary. Cannabis is widely used as a pain relieving agent, for the benefit of the patient.

Cannabis drug

Opioids and cannabinoids are helpful for the treatment of ANXIETY, DEPRESSION, and sleep in trial of medical cannabis, euphoria is often scored as an adverse effect. Online Medical Dispensary and Medical Dispensaries provide Medical Cannabis for treatments. The only way to receive medical cannabis is by getting a recommendation from your doctor.  Most doctors are helping people understand the many benefits of medical cannabis. The population in the United States is becoming more aware of the beneficial impact of medical cannabis.

You can buy Medical Marijuana after you receive a recommendation from your physician. It the digital age you can also buy Cannabis online from an online dispensary. Medical Marijuana Delivery services are very popular in California. Medical cannabis can really help alleviate stress and pain in cancer patients. Patients are describing overwhelming positive result, after using medical cannabis. Please consult your physician before using any form of Medical Cannabis.

14 thoughts on “Opioid & Cannabinoid Pharmacokinetic Interactions of Cannabis Drug”

  1. Great read. I didn’t know cancer patients where using medical marijuana to relieve their pain. I’m so happy I found this website. Very informative. Thanks for the information and great read

  2. I have done a lot of research on Dr. Donald Abrams. Thanks for bringing his research further into the light. Love the articles, keep up the great work, looking forward to seeing your next article

  3. I’ve seen people online saying that marijuana has cured their cancer. I think that’s a little far fetched but, I can certainly see how marijuana may help cancer patients with pain relief. Thanks for sharing this PotValet.

  4. Thank you for sharing this valuable information about Dr. Donald Abrams research on Marijuana. More people need to become aware of his groundbreaking work. Very informative article, thanks for sharing

  5. Hi,

    I am an opiate/opiod dependent individual that got addicted to the ‘feeling’ after many accidents skateboarding, surfing, and snowboarding. I need THC and CDB more now than ever, and it really pisses me off to see dispensaries acting like they are HELPING when they are charging street price ($40 for an 1/8th??? WHATT??? Cant afford you!) And where to dispensaries get off having retarded ass stoners pick up the phone like “yeah dude, $80 a gram, this wax is bomb” but your TOO FUCKING RETARDED TO test it…..

    1. Thanks for your great message Nick. We do believe we offer much more competitive prices than anyone on the market. We have some 1/8th’s that are only $20

      We have very high quality Wax, which we have tested and make ourselves. Some of the wax is only $35 a gram.

      We also provide a free gram of Flower, with every order

      We do need to pay our delivery driver and costs out of pocket to produce the medicine

      Thanks for your great comment and I think a lot more collectives should lower their prices, as we have :)

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